A PROTOCOL FOR FABRICATION AND ON-CHIP CELL CULTURE TO RECREATE PAH-AFFLICTED PULMONARY ARTERY ON A MICROFLUIDIC DEVICE

A Protocol for Fabrication and on-Chip Cell Culture to Recreate PAH-Afflicted Pulmonary Artery on a Microfluidic Device

Pulmonary arterial hypertension (PAH) is a rare pulmonary vascular disease that affects people of all ethnic origins and age groups including newborns.In PAH, pulmonary arteries and arterioles undergo a series of pathological changes including remodeling of the entire pulmonary vasculatures and extracellular matrices, mis-localized growth of pulmon

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Elevated inflammatory responses and targeted therapeutic intervention in a preclinical mouse model of ataxia-telangiectasia lung disease

Abstract Ataxia-telangiectasia (A-T) is an autosomal recessive, multisystem disorder characterized by cerebellar degeneration, cancer predisposition, and immune system defects.A major cause of mortality in A-T patients is severe pulmonary disease; however, the underlying causes of the lung complications are poorly understood, and there are currentl

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The history and development of penile prosthesis usage

In this paper, we review the current knowledge about surgical procedures for prosthetic penis.Phalloprosthetic operation is the most effective method of reinstatement the function of Storage Pier the penis, in addition endoprosthetic of neofallos often performed in patients after reconstruction of the penis, with the aim of improving its rigidity.T

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